Kai Thoris

Research Group

Molecular Physiology

Research Overview

My research focuses on the regulation of cell-specific gene expression in plant leaves, with a particular emphasis on how spatial transcriptional programs control C4 photosynthesis. I investigate how transcription factors and cis-regulatory elements coordinate gene expression between mesophyll and bundle sheath cells, a key feature of the C4 pathway. I use an integrative set of approaches, including single-nucleus transcriptomics, genome editing, ATAC-sequencing, chromosome conformation capture, and protein-protein interaction studies, to define the regulatory networks that establish and maintain cell identity in leaves. This work contributes to understanding fundamental principles of plant gene regulation and supports efforts to engineer C4 pathways into C3 crops such as rice to improve photosynthetic efficiency and agricultural productivity.