University of Cambridge
Cambridge CB2 3EA
Chiara joined the lab in 2014 after Marie Curie and BBSRC ERA-PG Post Doctoral fellowships with Brendan Davies at the University of Leeds. She completed her studies at the University of Milan where she obtained her PhD working with Lucia Colombo and Martin Kater.
During her PhD and Post Doctoral fellowships Chiara worked on transcription factors involved in several aspects of plant reproductive development and she developed a strong interest in their evolution.
Her current project investigates the evolution of the MYB-bHLH-WD40 (MBW) transcriptional complex that regulates the specification of cellular identity and anthocyanin biosynthesis. In collaboration with Sam Brockington she is using sequencing data from the 1KP project to analyse the evolution of the MYB, bHLH and WD40 protein families that form the MBW complex. By comparing proteins, DNA sequences and functional data in land plants she aims to elucidate the evolution of this multimeric complex, assessing when and how it originated, and how novel functional roles have arisen through molecular evolution.
Airoldi CA, McKay M, Davies B. MAF2 Is Regulated by Temperature-Dependent Splicing and Represses Flowering at Low Temperatures in Parallel with FLM. PLoS One. 2015 May 8;10(5):e0126516.
Glover BJ, Airoldi CA, Brockington SF, Fernández-Mazuecos M, Martínez-Pérez C, Mellers G, Moyroud E, Taylor L. How have advances in our understanding of flower development influenced our understanding of floral evolution? Int. J. Plant Sci. 2015 Apr 176(4):000–000.
Airoldi CA, Davies B. Gene duplication and the evolution of MADS-box transcription factors. J. Genet. Genomics. 2012 Apr 20;39(4):157-65.
Airoldi CA, Bergonzi S, Davies B. Single amino acid change alters the ability to specify male or female organ identity. PNAS. 2010 Nov 2;107(44):18898-902.
Bemer M, Heijmans K, Airoldi C, Davies B, Angenent GC. An atlas of type I MADS box gene expression during female gametophyte and seed development in Arabidopsis. Plant Physiol. 2010 Sep;154(1):287-300.
Airoldi CA. Determination of sexual organ development. Sex Plant Reprod. 2010 Mar;23(1):53-62.
Airoldi CA, Della Rovere F, Falasca G, Marino G, Kooiker M, Altamura MM, Citterio S, Kater MM. The Arabidopsis BET bromodomain factor GTE4 is involved in maintenance of the mitotic cell cycle during plant development. Plant Physiol. 2010 Mar;152(3):1320-34.
Kaufmann K, Muiño JM, Jauregui R, Airoldi CA, Smaczniak C, Krajewski P, Angenent GC. Target genes of the MADS transcription factor SEPALLATA3: integration of developmental and hormonal patways in the Arabidopsis flower. PLoS Biol. 2009 Apr 21;7(4):e1000090.
Kooiker M, Airoldi CA, Losa A, Manzotti PS, Finzi L, Kater MM, Colombo L. BASIC PENTACYSTEINE1, a GA binding protein that induces conformational changes in the regulatory region of the homeotic Arabidopsis gene SEEDSTICK. Plant Cell. 2005 Mar;17(3):722-9.